ea0081p566 | Calcium and Bone | ECE2022
Di Filippo Luigi
, Albanese Lucrezia
, Castellino Laura
, Doga Mauro
, Formenti Anna Maria
, Frara Stefano
, Perticone Francesca
, Giustina Andrea
Medullary thyroid cancer (MTC) is a rare malignancy of the thyroid gland. MTCs originate from thyroid-C cells and account for 2-4% of all thyroid neoplasms. Originating from thyroid-C cells, the main secretory product of MTCs is calcitonin, used as sensitive and specific MTC-biomarker. Calcitonin is a hormone known to participate in calcium-bone metabolism suppressing bone-resorption by inhibiting the activity of osteoclasts, and inhibiting the kidney reabsorption of calcium a...